# 1st Optimal reviews (2026): GLP-1 telehealth sellers | This GLP A lab-led coaching membership with GLP-1 prescribing inside it, where the membership has a price and the drug does not. Publisher: This GLP Editorial Team Canonical: https://thisglp.com/reviews/1st-optimal Updated: 2026-10-26 By [This GLP Editorial Team](https://thisglp.com/about) · Updated September 2026 Membership priced, medication not # 1st Optimal review A lab-led coaching membership with GLP-1 prescribing inside it, where the membership has a price and the drug does not. ## The verdict 1st Optimal publishes $99 a month for its Weight Loss Care membership. The medication is invoiced separately, and no figure for it appears anywhere on the site. That makes the membership the only cost a reader can know before joining. **Disclosure:** This GLP is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. The order on this page is not commercial, and a commission never changes what we write about a provider. [How we make money](https://thisglp.com/disclosures). Category GLP-1 telehealth Molecule Semaglutide Form Injection Prescription Required Labs Included 1st Optimal is a Michigan-based functional medicine service that sells monthly care memberships. Weight loss is one of several plans, beside hormone, menopause and peptide care. GLP-1 therapy is offered within that weight-loss plan. 1. ## Who writes the prescription, and what do they see? The site states that a licensed provider reviews lab results and discusses a treatment plan after an initial consultation. A prescription, if one is written, goes electronically to a partner pharmacy. The individual prescriber is not named on the plan pages, though a nurse practitioner appears in the site's podcast. Labs come first. The membership covers consultations, lab testing, shipping and medical supplies, plus monthly coaching on nutrition and exercise. Billing is month to month, drafted on the 1st or the 16th, with no long-term contract stated. The FAQ says pharmacy partners typically ship within 14 business days, which is slower than most mail-order GLP-1 sellers state. 2. ## What happens when the dose goes up? The weight-loss page describes protocols that use minimum effective doses, adjusted against labs and symptoms. No dose schedule is published. Because the medication price is not published either, what a dose increase does to the monthly cost is not stated. 3. ## What the price includes $99 a month buys the membership. Prescriptions, labs and supplements are invoiced separately, about three weeks before each refill for existing patients. The FAQ promises a reduced members-only rate on treatments but prints no rate. A total monthly cost cannot be worked out from the site. 4. ## What it claims, and what it cites The plan pages describe GLP-1s as FDA-approved medications and list weekly injections, daily tablets and combination therapies. They do not name the molecule, say whether it is branded or compounded, or name the partner pharmacy. Compounded preparations are not FDA-approved. ## Where it holds up, and where it does not - Strength: Month-to-month billing, no contract stated - Strength: Labs and consultations sit inside the membership - Strength: Coaching is part of the plan, not an add-on - Strength: Cancellation is described step by step - Limitation: No medication price is published - Limitation: The molecule is not named on the plan pages - Limitation: Shipping can take 14 business days - Limitation: States are given only on request ## What the evidence says about this kind of treatment The assessment above is about 1st Optimal. These are about the drugs it sells, and they are traced to the primary literature. - [What happens to the dose, and to the side effects, over the first twenty weeks?](https://thisglp.com/research/how-long-does-nausea-last-on-a-glp1) - [How much of the weight lost is muscle, and what changes that?](https://thisglp.com/research/muscle-loss-on-glp1) - [What does the trial evidence show when treatment stops?](https://thisglp.com/research/stopping-glp1-and-weight-regain) Right for A reader who wants labs and coaching around a prescription, and will ask for the drug price before paying. Wrong for A reader comparing all-in monthly GLP-1 prices, since only the membership has one here. ## The evidence behind what 1st Optimal prescribes These studies examine the medicines, not this provider. Results with approved products do not establish the quality or effectiveness of a seller’s compounded formulation. - [Cochrane Review of Semaglutide for Obesity: 18 Trials Graded](https://thisglp.com/research/semaglutide-cochrane-review) A 2025 Cochrane review pooled eighteen randomized trials. The weight figure is high certainty and smaller than the marketing, and almost everything else is graded lower. ## How 1st Optimal compares | Seller | Who it suits | Go | | --- | --- | --- | | Found | Readers who will commit to a longer term and want coaching and membership inside one figure | | | Measured | Readers ready to commit to a term who know which rung the lead figure is | | | Calibrate Health | Insured buyers who want coaching and insurance handling alongside a prescription | | [Compare all providers side by side →](https://thisglp.com/best) More GLP-1 telehealth sellers reviews: [Eden](https://thisglp.com/reviews/eden) [Embody](https://thisglp.com/reviews/embody) [Enhance MD](https://thisglp.com/reviews/enhance-md) [Gala](https://thisglp.com/reviews/gala) [HealthRX](https://thisglp.com/reviews/healthrx) [HumeCare+](https://thisglp.com/reviews/humecare) Sponsored alternative SkinnyRx Readers choosing tirzepatide, the one line with a published standing rate ## Frequently asked Does $99 a month include the GLP-1? No. The $99 is the Weight Loss Care membership. The FAQ says prescriptions are invoiced separately, and no medication price is published. Which states does 1st Optimal cover? It does not list them. The FAQ asks readers to email member support for the current list. Is there a commitment? The FAQ says the membership is month to month and renews until a change request is filed. Or [compare every seller we cover](https://thisglp.com/best). **Research, not medical advice.** This GLP is independent and educational. Nothing here is a substitute for individualized care from a licensed clinician, and reading it creates no doctor–patient relationship. Talk to your own provider before starting, stopping, or changing any medication, peptide, or therapy. See our [methodology](https://thisglp.com/methodology) and [terms](https://thisglp.com/terms).