# He & She MD reviews (2026): GLP-1 telehealth sellers | This GLP Both injection rates are annual plans billed in a single payment, and the oral figure is an introductory rate that renews twenty percent higher. Publisher: This GLP Editorial Team Canonical: https://thisglp.com/reviews/he-and-she-md Updated: 2026-10-28 By [This GLP Editorial Team](https://thisglp.com/about) · Updated September 2026 A year up front, or a renewal # He & She MD review Both injection rates are annual plans billed in a single payment, and the oral figure is an introductory rate that renews twenty percent higher. ## The verdict He & She MD advertises $99 a month for injected semaglutide and $159 for tirzepatide, and both require a year paid at once — $1,188 and $1,908. Its oral line runs $199 for six months and then renews at $239. **Disclosure:** This GLP is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. The order on this page is not commercial, and a commission never changes what we write about a provider. [How we make money](https://thisglp.com/disclosures). Category GLP-1 telehealth Molecule Semaglutide · Tirzepatide Form Injection · Oral States 50 Injection From $199/mo Oral From $239/mo Prescription Required Compounded Yes — not FDA-approved Availability 50 states He & She MD sells both molecules by injection on annual plans billed up front, alongside an oral program priced as an introductory half-year that renews at a higher rate, with coverage across 50 states. 1. ## Who writes the prescription, and what do they see? A prescription precedes dispensing, and the pages present program cards and footnotes rather than describing who reviews a case or how often. The oral line's renewal terms live in a footnote rather than on the card. Annual prepay at a low headline is a defensible offer, and the totals are published rather than hidden. What the pages do less well is separate the two numbers in the banner, where a struck-through monthly figure and an annual one sit in the same sentence as though they were alternatives. 2. ## What happens when the dose goes up? Nothing published states what any of these figures does as a dose climbs, which matters most on the annual plans: a buyer has committed twelve months before discovering whether the rate survives an escalation. 3. ## What the price includes A year of injected semaglutide is $1,188 and tirzepatide $1,908, both due at signup rather than monthly. The oral program is $1,194 for its first six months and $1,434 for every six after, so a full year at the renewal rate is $2,868. Budgeting the oral at its introductory figure understates a second year by $480. 4. ## What it claims, and what it cites The lines are compounded rather than manufactured, prepared to order by a pharmacy the pages do not name, and the FDA does not review a compounded preparation before it is dispensed. ## Where it holds up, and where it does not - Strength: Annual totals are published, not just rates - Strength: Coverage across 50 states - Strength: An oral program is offered separately - Strength: The renewal rate appears in a footnote - Limitation: Both injection rates need a year at once - Limitation: The oral renews about 20% higher - Limitation: The banner shows two prices in one line - Limitation: Refunds inside an annual term are unstated ## What the evidence says about this kind of treatment The assessment above is about He & She MD. These are about the drugs it sells, and they are traced to the primary literature. - [What happens to the dose, and to the side effects, over the first twenty weeks?](https://thisglp.com/research/how-long-does-nausea-last-on-a-glp1) - [How much of the weight lost is muscle, and what changes that?](https://thisglp.com/research/muscle-loss-on-glp1) - [What does the trial evidence show when treatment stops?](https://thisglp.com/research/stopping-glp1-and-weight-regain) Right for A reader who can pay a year in advance and wants the annual total published rather than implied. Wrong for A reader reading the oral $199 as a rate that holds, or anyone who cannot commit twelve months at signup. ## The evidence behind what He & She MD prescribes These studies examine the medicines, not this provider. Results with approved products do not establish the quality or effectiveness of a seller’s compounded formulation. - [Cochrane Review of Semaglutide for Obesity: 18 Trials Graded](https://thisglp.com/research/semaglutide-cochrane-review) A 2025 Cochrane review pooled eighteen randomized trials. The weight figure is high certainty and smaller than the marketing, and almost everything else is graded lower. - [Tirzepatide vs Semaglutide: Which Works Better for Weight Loss?](https://thisglp.com/research/tirzepatide-vs-semaglutide-which-works-better) In a 72-week randomized trial at weight-management doses, weight fell 20.2 percent on tirzepatide and 13.7 percent on semaglutide. Routine-care studies found a smaller gap, three to four points. ## How He & She MD compares | Seller | Who it suits | Go | | --- | --- | --- | | Try Ageless | Readers willing to price the same product twice before buying it once | | | MEDVi | Readers who want the injected line, where the card figure is the medicine's figure | | | Roboclinic | Readers ready to commit a full year and wanting the discount that buys | | [Compare all providers side by side →](https://thisglp.com/best) More GLP-1 telehealth sellers reviews: [Belle Health](https://thisglp.com/reviews/belle-health) [bmiMD](https://thisglp.com/reviews/bmimd) [Bodybuilding Health+](https://thisglp.com/reviews/bodybuilding-health-plus)[Collective](https://thisglp.com/reviews/collective) [CoreAge Rx](https://thisglp.com/reviews/coreage-rx) [Direct Meds](https://thisglp.com/reviews/direct-meds) Sponsored alternative SkinnyRx Readers choosing tirzepatide, the one line with a published standing rate ## Frequently asked What does $99 a month actually require? A year paid in a single payment of $1,188. There is no month-to-month route to that figure. Does the oral price hold? No. $199 covers six months, after which the program renews at $1,434 per six months, which is $239 a month. What does a full year of tirzepatide cost? $1,908, billed up front at signup rather than spread across the year. Is He & She MD legit? He & She MD is a GLP-1 telehealth sellers service. Its stated availability: 50 states. What our record does not establish: whether it bills insurance and how its intake works. Ask for those in writing before you pay. Is He & She MD expensive compared with other GLP-1 telehealth sellers? He & She MD publishes a starting figure of $199/mo. Across the 402 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $49 to $525.42 with a median of $190, which puts He & She MD above the median. The other 178 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes. Or [compare every seller we cover](https://thisglp.com/best). **Research, not medical advice.** This GLP is independent and educational. Nothing here is a substitute for individualized care from a licensed clinician, and reading it creates no doctor–patient relationship. Talk to your own provider before starting, stopping, or changing any medication, peptide, or therapy. See our [methodology](https://thisglp.com/methodology) and [terms](https://thisglp.com/terms).