# Lean Rx reviews (2026): GLP-1 telehealth sellers | This GLP Every plan is billed in four-week fills. The one rung without a lock-in adds shipping. Publisher: This GLP Editorial Team Canonical: https://thisglp.com/reviews/lean-rx Updated: 2026-10-28 By [This GLP Editorial Team](https://thisglp.com/about) · Updated September 2026 Four-week fills, shipping extra # Lean Rx review Every plan is billed in four-week fills. The one rung without a lock-in adds shipping. ## The verdict Lean Rx charges $450 for four weeks of compounded semaglutide, plus $35 shipping. That is $485 per fill. Tirzepatide is $599 plus shipping, or $634 per fill. Fills come every four weeks, thirteen a year. So a calendar month costs $525.42 and $686.83. Both are paid in full with no commitment. **Disclosure:** This GLP is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. The order on this page is not commercial, and a commission never changes what we write about a provider. [How we make money](https://thisglp.com/disclosures). Category GLP-1 telehealth Molecule Semaglutide · Tirzepatide Form Injection From From $525.42/mo Prescription Required Compounded Yes — not FDA-approved Lean Rx sells compounded semaglutide and tirzepatide by injection. It sells compounded medications only. Every plan is billed in four-week fills. Longer prepaid plans lower the average cost per vial. 1. ## Who writes the prescription, and what do they see? The first step is a brief online consultation. A medical history form follows. A licensed provider then holds a telehealth call. The provider prescribes a plan if appropriate. No provider is named. The buyer picks a program length after the call. Four options are offered per molecule. A pay-as-you-go subscription bills every four weeks. It cannot be canceled until 24 weeks. The single four-week fill carries no commitment. Longer plans are prepaid and ship free. 2. ## What happens when the dose goes up? A typical tirzepatide schedule is published in units, not milligrams. It runs 25 units a week for weeks one to four, then 50 units. A dose above 50 units a week needs an extra vial. That vial is billed on top, every four weeks. Dose is a price variable here. 3. ## What the price includes This site ranks the rate a buyer pays without committing. For Lean Rx that is the four-week fill. Each fill is charged $485 for semaglutide and $634 for tirzepatide, shipping included. Thirteen fills fall in a year. Per calendar month that is $525.42 and $686.83, the figures ranked here. The pay-as-you-go rate is lower but locks in 24 weeks. The 12- and 48-week plans are lower again, paid up front. Tirzepatide costs $149 more per fill. 4. ## What it claims, and what it cites Both products are compounded, per the seller's own FAQ. They come from state-licensed compounding pharmacies or 503B outsourcing facilities. Compounded drugs are not FDA-approved. The pharmacy is not named. ## Where it holds up, and where it does not - Strength: A no-commitment fill on both molecules - Strength: Dosing schedule published in units - Strength: Longer plans ship free - Strength: The seller says outright the drugs are compounded - Limitation: Shipping adds $35 to the no-commitment fill - Limitation: Pay-as-you-go locks in 24 weeks - Limitation: Higher doses cost an extra vial - Limitation: Billing runs on four weeks, not months ## What the evidence says about this kind of treatment The assessment above is about Lean Rx. These are about the drugs it sells, and they are traced to the primary literature. - [What happens to the dose, and to the side effects, over the first twenty weeks?](https://thisglp.com/research/how-long-does-nausea-last-on-a-glp1) - [How much of the weight lost is muscle, and what changes that?](https://thisglp.com/research/muscle-loss-on-glp1) - [What does the trial evidence show when treatment stops?](https://thisglp.com/research/stopping-glp1-and-weight-regain) Right for A buyer who wants a single fill with no subscription before choosing a plan. Wrong for A buyer on a high dose, where the extra vial raises every fill. ## The evidence behind what Lean Rx prescribes These studies examine the medicines, not this provider. Results with approved products do not establish the quality or effectiveness of a seller’s compounded formulation. - [Cochrane Review of Semaglutide for Obesity: 18 Trials Graded](https://thisglp.com/research/semaglutide-cochrane-review) A 2025 Cochrane review pooled eighteen randomized trials. The weight figure is high certainty and smaller than the marketing, and almost everything else is graded lower. - [Tirzepatide vs Semaglutide: Which Works Better for Weight Loss?](https://thisglp.com/research/tirzepatide-vs-semaglutide-which-works-better) In a 72-week randomized trial at weight-management doses, weight fell 20.2 percent on tirzepatide and 13.7 percent on semaglutide. Routine-care studies found a smaller gap, three to four points. ## How Lean Rx compares | Seller | Who it suits | Go | | --- | --- | --- | | Alegro Health | Buyers trying a GLP-1 for two months before committing to a rate | | | Gimme Care | Buyers who want the monthly price fixed while the dose climbs | | | Spry | Buyers who can read a four-week billing cycle as thirteen charges rather than twelve | | [Compare all providers side by side →](https://thisglp.com/best) More GLP-1 telehealth sellers reviews: [PrideRx](https://thisglp.com/reviews/priderx) [Primary Clinic (Direct GLP)](https://thisglp.com/reviews/primary-clinic)[Prime Doctor RX](https://thisglp.com/reviews/prime-doctor-rx) [Prime Health](https://thisglp.com/reviews/prime-health) [Queen RX](https://thisglp.com/reviews/queen-rx) [QuickMD](https://thisglp.com/reviews/quickmd) Sponsored alternative SkinnyRx Readers choosing tirzepatide, the one line with a published standing rate ## Frequently asked Why $525.42 and not $450? The four-week fill is $450 plus a required $35 overnight shipping charge, so each fill is $485. Fills come every four weeks, thirteen a year, which is $525.42 a calendar month. Is there a cheaper recurring plan? Yes, pay-as-you-go. It bills every four weeks and cannot be canceled before 24 weeks. Does a higher dose cost more? Yes. Above 50 units a week, an extra vial is billed every four weeks. Is Lean Rx expensive compared with other GLP-1 telehealth sellers? Lean Rx publishes a starting figure of $525.42/mo. Across the 402 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $49 to $525.42 with a median of $190, which puts Lean Rx above the median. The other 178 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes. Or [compare every seller we cover](https://thisglp.com/best). **Research, not medical advice.** This GLP is independent and educational. Nothing here is a substitute for individualized care from a licensed clinician, and reading it creates no doctor–patient relationship. Talk to your own provider before starting, stopping, or changing any medication, peptide, or therapy. See our [methodology](https://thisglp.com/methodology) and [terms](https://thisglp.com/terms).