# PlushCare reviews (2026): GLP-1 telehealth sellers | This GLP

The advertised cash-pay figure buys the 0.25 mg starting dose, and every maintenance dose is priced above it.

Publisher: This GLP Editorial Team
Canonical: https://thisglp.com/reviews/plushcare
Updated: 2026-10-28

By [This GLP Editorial Team](https://thisglp.com/about) · Updated September 2026 Starting dose only at $149

# PlushCare review

The advertised cash-pay figure buys the 0.25 mg starting dose, and every maintenance dose is priced above it.

## The verdict

PlushCare advertises compounded semaglutide at $149 a month cash-pay, and that figure covers the 0.25 mg starting dose only. Every higher dose is $299. No compounded tirzepatide price is published, and insurance is accepted on a separate basis.

**Disclosure:** This GLP is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. The order on this page is not commercial, and a commission never changes what we write about a provider. [How we make money](https://thisglp.com/disclosures).

Category

GLP-1 telehealth

Molecule

Semaglutide · Tirzepatide

Form

Injection

States

50

From

From $149/mo

Prescription

Required

Compounded

Yes — not FDA-approved

PlushCare sells compounded semaglutide as a weekly injection across fifty states. The cash-pay figures read $149 at 0.25 mg and $299 at every dose from 0.5 mg to 2.4 mg. Its compounded tirzepatide page now redirects to a Mounjaro page with no compounded price. Insurance is accepted as a separate route to treatment.

1.  ## Who writes the prescription, and what do they see?
    
    Treatment runs through a clinician visit rather than a form alone, and insurance is billed where it applies. That is a different model from a flat-fee compounding seller with no visit in it. What the visit covers, and how often it repeats, is not published. The two routes are priced separately and a reader chooses one at intake.
    
    Care is arranged remotely and the prescription follows the visit. The cash-pay figure and the insurance route answer different questions for different readers. A reader with coverage is comparing a copay against $149 rather than comparing sellers. A reader without coverage is comparing $149 against a market where most rates are flat.
    
2.  ## What happens when the dose goes up?
    
    This is the seller's weak point and it is stated plainly. $149 buys 0.25 mg, and 0.25 mg is a four-week starting dose for almost everyone. Every dose from 0.5 mg to 2.4 mg is $299, printed in the same sentence as the entry figure. A reader planning a year should treat $149 as the first month and $299 as the standing rate.
    
3.  ## What the price includes
    
    $149 is real and it is narrow. Sellers charging a flat $199 hold that figure at 2.4 mg, where PlushCare charges $299. No compounded tirzepatide figure is published at all. Insurance may change the semaglutide figure and is settled case by case rather than published.
    
4.  ## What it claims, and what it cites
    
    The [semaglutide](https://thisglp.com/research/semaglutide-cochrane-review) is compounded, so a pharmacy prepares it and no regulator reviews the finished vial. The published weight-change results for semaglutide came from the approved product at maintenance doses, not at 0.25 mg. A starting dose is a titration step rather than a treatment dose. What four weeks at 0.25 mg produces on its own was not measured as an endpoint.
    

## Where it holds up, and where it does not

-   Strength: Says what the entry figure buys
-   Strength: Insurance accepted as a separate route
-   Strength: Prescription follows a clinician visit
-   Limitation: Maintenance doses cost $299 a month
-   Limitation: No compounded tirzepatide price published

## What the evidence says about this kind of treatment

The assessment above is about PlushCare. These are about the drugs it sells, and they are traced to the primary literature.

-   [What happens to the dose, and to the side effects, over the first twenty weeks?](https://thisglp.com/research/how-long-does-nausea-last-on-a-glp1)
-   [How much of the weight lost is muscle, and what changes that?](https://thisglp.com/research/muscle-loss-on-glp1)
-   [What does the trial evidence show when treatment stops?](https://thisglp.com/research/stopping-glp1-and-weight-regain)

Right for

A reader with insurance who wants a clinician visit in the loop, and who reads $149 as a starting-dose figure rather than a standing one.

Wrong for

A reader budgeting a year at one rate, because the advertised figure covers 0.25 mg and every dose above it is $299.

## The evidence behind what PlushCare prescribes

These studies examine the medicines, not this provider. Results with approved products do not establish the quality or effectiveness of a seller’s compounded formulation.

-   [Cochrane Review of Semaglutide for Obesity: 18 Trials Graded](https://thisglp.com/research/semaglutide-cochrane-review)
    
    A 2025 Cochrane review pooled eighteen randomized trials. The weight figure is high certainty and smaller than the marketing, and almost everything else is graded lower.
    
-   [Tirzepatide vs Semaglutide: Which Works Better for Weight Loss?](https://thisglp.com/research/tirzepatide-vs-semaglutide-which-works-better)
    
    In a 72-week randomized trial at weight-management doses, weight fell 20.2 percent on tirzepatide and 13.7 percent on semaglutide. Routine-care studies found a smaller gap, three to four points.
    

## How PlushCare compares

| Seller | Who it suits | Go |
| --- | --- | --- |
| Liberty | A reader who wants to know what kind of facility made the vial, and will accept a mid-market rate to get that in writing. |  |
| Pallas Health | A reader past the opening quarter who wants check-ins priced in, not billed per visit. |  |
| Harper Meds | A reader who wants a clinician, a prescription and the medication under one charge, with no term to commit to before reaching the published rate. |  |

[Compare all providers side by side →](https://thisglp.com/best)

More GLP-1 telehealth sellers reviews: [Vitakey](https://thisglp.com/reviews/vitakey) [Vital Step](https://thisglp.com/reviews/vital-step) [Vivanta Care](https://thisglp.com/reviews/vivanta-care) [VivioMD](https://thisglp.com/reviews/viviomd) [welludr.](https://thisglp.com/reviews/wellmedr)[Yes Clinic](https://thisglp.com/reviews/yes-clinic)

Sponsored alternative

SkinnyRx

Readers choosing tirzepatide, the one line with a published standing rate

## Frequently asked

Is $149 what a maintenance dose costs?

No. PlushCare states that the $149 cash-pay figure buys the 0.25 mg starting dose, and that 0.5 mg through 2.4 mg cost $299 a month.

How long does anyone stay at 0.25 mg?

The approved semaglutide schedule holds 0.25 mg for four weeks before the first increase. A reader on that schedule is past the advertised figure by month two.

Does insurance change the price?

Insurance is accepted on a separate basis from the cash-pay figure, and what it leaves a patient to pay is settled case by case rather than published.

Is PlushCare expensive compared with other GLP-1 telehealth sellers?

PlushCare publishes a starting figure of $149/mo. Across the 402 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $49 to $525.42 with a median of $190, which puts PlushCare below the median, toward the cheaper end. The other 178 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Or [compare every seller we cover](https://thisglp.com/best).

**Research, not medical advice.** This GLP is independent and educational. Nothing here is a substitute for individualized care from a licensed clinician, and reading it creates no doctor–patient relationship. Talk to your own provider before starting, stopping, or changing any medication, peptide, or therapy. See our [methodology](https://thisglp.com/methodology) and [terms](https://thisglp.com/terms).
