# Yes Clinic reviews (2026): GLP-1 telehealth sellers | This GLP

Yes Clinic makes the product and price structure relatively easy to identify. Clinical follow-up still deserves a direct conversation.

Publisher: This GLP Editorial Team
Canonical: https://thisglp.com/reviews/yes-clinic
Updated: 2026-10-26

By [This GLP Editorial Team](https://thisglp.com/about) · Updated October 2026 A semaglutide program with a clearly identified compounded injectable and a choice of monthly or longer supply purchases.

# Yes Clinic review

Yes Clinic makes the product and price structure relatively easy to identify. Clinical follow-up still deserves a direct conversation.

## The verdict

The named semaglutide and vitamin B12 formulation, flat-dose statement and separate plan lengths are useful disclosures. They do not establish the quality or frequency of ongoing care.

**Disclosure:** This GLP is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. The order on this page is not commercial, and a commission never changes what we write about a provider. [How we make money](https://thisglp.com/disclosures).

Category

GLP-1 telehealth

Molecule

Semaglutide

Form

Injection

Dose pricing

Flat across doses

Prescription

Required

Compounded

Yes — not FDA-approved

Yes Clinic provides an online route to independent medical review and pharmacy fulfillment. Its semaglutide page describes a compounded injectable containing semaglutide and vitamin B12.

1.  ## Who writes the prescription, and what do they see?
    
    An independent licensed clinician decides whether treatment is appropriate. Ask which medical practice is responsible for follow-up and how to reach it after medication arrives.
    
    Consultation is included on the product page, but the public offer does not fully specify scheduled follow-up or response times. Clarify how symptoms, laboratory needs and prescription changes are handled.
    
2.  ## What happens when the dose goes up?
    
    The product page says pricing remains the same at every dose. A flat price is a financial term, not a reason to increase a dose; changes still require individualized clinical guidance.
    
3.  ## What the price includes
    
    Monthly, three-month and six-month purchases are displayed separately. Longer options involve a larger upfront purchase, while terms distinguish recurring subscriptions from plans that do not renew.
    
4.  ## What it claims, and what it cites
    
    The reviewed product is compounded [semaglutide](https://thisglp.com/research/semaglutide-cochrane-review) with vitamin B12, administered by injection. It is not an FDA-approved version of a branded semaglutide medicine.
    

## Where it holds up, and where it does not

-   Strength: Identifies the compounded formulation
-   Strength: States that price does not rise with dose
-   Limitation: Follow-up frequency needs confirmation
-   Limitation: Longer supplies increase the upfront commitment

## What the evidence says about this kind of treatment

The assessment above is about Yes Clinic. These are about the drugs it sells, and they are traced to the primary literature.

-   [What happens to the dose, and to the side effects, over the first twenty weeks?](https://thisglp.com/research/how-long-does-nausea-last-on-a-glp1)
-   [How much of the weight lost is muscle, and what changes that?](https://thisglp.com/research/muscle-loss-on-glp1)
-   [What does the trial evidence show when treatment stops?](https://thisglp.com/research/stopping-glp1-and-weight-regain)

Right for

Adults seeking a clearly identified semaglutide formulation and willing to confirm the follow-up plan.

Wrong for

Anyone choosing primarily on a longer-supply discount before understanding treatment tolerance or refund limits.

## The evidence behind what Yes Clinic prescribes

These studies examine the medicines, not this provider. Results with approved products do not establish the quality or effectiveness of a seller’s compounded formulation.

-   [Cochrane Review of Semaglutide for Obesity: 18 Trials Graded](https://thisglp.com/research/semaglutide-cochrane-review)
    
    A 2025 Cochrane review pooled eighteen randomized trials. The weight figure is high certainty and smaller than the marketing, and almost everything else is graded lower.
    

## How Yes Clinic compares

| Seller | Who it suits | Go |
| --- | --- | --- |
| SkinnyRx | Readers choosing tirzepatide, the one line with a published standing rate |  |
| ShedRx | Readers willing to telephone a seller and ask which published fee is the real one |  |
| RxSpan MD | Buyers who want the standing rate, the pharmacy and the prescriber named before signing up |  |

[Compare all providers side by side →](https://thisglp.com/best)

More GLP-1 telehealth sellers reviews: [KairoRx](https://thisglp.com/reviews/kairorx) [KIN Health](https://thisglp.com/reviews/kin-health) [Klarity Health](https://thisglp.com/reviews/klarity-health) [Klinic](https://thisglp.com/reviews/klinic) [Kova](https://thisglp.com/reviews/kova) [LifeVine Wellness](https://thisglp.com/reviews/lifevine-wellness)

Sponsored alternative

SkinnyRx

Readers choosing tirzepatide, the one line with a published standing rate

## Frequently asked

Does flat pricing determine the dose?

No. The flat-price statement concerns cost. The clinician must decide the appropriate prescription.

What formulation is listed?

The reviewed product page describes injectable compounded semaglutide with vitamin B12, not an FDA-approved branded pen.

## Sources for this review

Provider information checked October 26, 2026. Terms can change.

-   [Official service overview](https://yesclinic.com/)
-   [Official program and terms](https://yesclinic.com/terms-of-use/)
-   [Official program and terms](https://yesclinic.com/product/semaglutide/)

Or [compare every seller we cover](https://thisglp.com/best).

**Research, not medical advice.** This GLP is independent and educational. Nothing here is a substitute for individualized care from a licensed clinician, and reading it creates no doctor–patient relationship. Talk to your own provider before starting, stopping, or changing any medication, peptide, or therapy. See our [methodology](https://thisglp.com/methodology) and [terms](https://thisglp.com/terms).
