Updated September 2026Renamed, pharmacies namedPiper review
The brand has changed; the company behind it and the prices have not.
The verdict
Piper now trades as Polly, and the old address redirects to the new one under the same corporate name. The catalog is unchanged: $135 a week for compounded semaglutide, $199 for compounded tirzepatide, with two compounding pharmacies named in the FAQ. That naming is the reason to read this one.
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- Category
- GLP-1 telehealth
- Molecule
- Semaglutide · Tirzepatide
- Form
- Injection
- Dose pricing
- Flat across doses
- States
- 50
- From
- From $146/mo
- Dose published
- No
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
- Pharmacy
- Named
- Availability
- All 50 states
Polly is a cash-pay telehealth platform selling compounded semaglutide and compounded tirzepatide by weekly injection. Sermorelin, a lipotropic blend and two NAD+ formats sit beside them. Access is stated for all fifty states. The footer names the operating company and the trading name it now uses.
Who writes the prescription, and what do they see?
The FAQ is unusually exact about the arrangement, and what it describes is a platform rather than a practice. Polly states it connects patients with independent licensed healthcare professionals, and that every medical evaluation, prescription and pharmacy service is provided by third parties. An independent provider reviews the intake and decides whether treatment is appropriate. No individual clinician or medical group is named.
Three steps run from online intake to delivery, with free next-day air shipping stated on every order. No membership fee and no lock-in are advertised. Insurance is not billed, though HSA and FSA reimbursement is described as possible. A patient portal carries follow-up messaging.
What happens when the dose goes up?
The catalog quotes one rate per molecule, with no dose tier beside it and no milligram figure anywhere. Treatment is described as adjusted by the provider as needed, which is a statement about oversight rather than about price. Whether the charge moves at a step up is not addressed on the page. Consistent pricing is advertised as a feature without being defined.
What the price includes
Each product card carries a single figure and the word weekly beneath it: $135 for semaglutide, $199 for tirzepatide. The peptide and NAD+ lines are priced the same way. No multi-month plan, prepay tier or renewal rate is published. What the fill covers in weeks is on the card; what it costs across a calendar year is not.
What it claims, and what it cites
Both GLP-1 lines are compounded rather than manufactured. The FAQ names two 503A compounding pharmacies and states they are overseen by state boards of pharmacy. Compounded preparations are not FDA-approved and are not reviewed by the FDA before dispensing.
Where it holds up, and where it does not
- Strength: Two compounding pharmacies are named
- Strength: No membership fee and no lock-in
- Strength: Free next-day shipping on every order
- Strength: The platform's third-party role is stated plainly
- Strength: Availability is claimed in all fifty states
- Limitation: The brand name has changed under the buyer
- Limitation: No multi-month or prepay rate is published
- Limitation: The fill is weekly, not a calendar month
- Limitation: No milligram dose appears on any card
- Limitation: No individual clinician is named
What the evidence says about this kind of treatment
The assessment above is about Piper. These are about the drugs it sells, and they are traced to the primary literature.
- Right for
- A buyer who wants the compounding pharmacy named before handing over a card.
- Wrong for
- A buyer who wants one accountable practice rather than a platform of third parties.
How Piper compares
| Seller | Who it suits | Go |
|---|---|---|
 TrueMe | Buyers in one of the six states it serves who want refund terms stated before the intake | See TrueMe → |
 FMmeds | Buyers who want one all-in figure and the compounding pharmacy named beside it | See FMmeds → |
| CLYR Health | Buyers who want the cost of each dose tier published before the first injection | See CLYR Health → |
More GLP-1 telehealth sellers reviews: TelePeptideTelos RxThe EditTMatesTransparent MedsTrimRx
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Check Bodybuilding Health+ availability →Frequently asked
- Is Polly the same company as Piper?
- Yes. The footer names one operating company trading under the Polly brand, and the Piper address redirects there.
- Which pharmacies fill these prescriptions?
- Polly names two 503A compounding pharmacies in its FAQ and states both are overseen by state boards of pharmacy.
- Who actually writes the prescription?
- An independent licensed provider, not Polly. Its FAQ states all clinical services are provided solely by third-party licensed professionals.
- Is Piper legit?
- Piper is a GLP-1 telehealth sellers service. Its stated availability: All 50 states. What our record does not establish: whether it bills insurance and how its intake works. Ask for those in writing before you pay.
- Is Piper expensive compared with other GLP-1 telehealth sellers?
- Piper publishes a starting figure of $146/mo. Across the 252 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $49 to $399 with a median of $178, which puts Piper below the median, toward the cheaper end. The other 19 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.