Updated September 2026One rate at every doseRylo Health review
The no-contract rate holds at every dose, and the filling pharmacy is named.
The verdict
Rylo Health charges $139 a month for compounded semaglutide, month to month. Tirzepatide is $229 a month on the same no-contract terms. Neither figure moves when the physician raises the dose.
Disclosure: This GLP is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. The order on this page is not commercial, and a commission never changes what we write about a provider. How we make money.
- Category
- GLP-1 telehealth
- Molecule
- Semaglutide · Tirzepatide
- Form
- Injection
- Dose pricing
- Flat across doses
- States
- 50
- From
- From $139/mo
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
- Pharmacy
- Named
- Availability
- All 50 states
Rylo Health sells compounded semaglutide and tirzepatide as once-weekly injections. Each product page has a monthly tab and a quarterly tab. The quarterly tab opens first, and the monthly tab carries the no-contract rate.
Who writes the prescription, and what do they see?
A US-licensed physician reviews each written intake within 24 hours. There is no video call at any point before prescribing. The FAQ names Lone Star Virtual Health PLLC as the clinical group. The reviewing physician is not named on the product pages.
The intake is a written questionnaire that takes about five minutes. A physician decides from the answers and the health history given. An approved order ships free and arrives in about two days. The seller states its care team checks in with each patient every month. Payment is refundable until a prescription is written.
What happens when the dose goes up?
The price does not change with the dose, and both product pages say so. The homepage shows a three-month ladder from 2.5 mg to 7.5 mg. Each month on that ladder costs $160, the quarterly tirzepatide rate. The seller states the physician adjusts the dose every month. No separate visit is described for a step up.
What the price includes
Month to month, semaglutide is $139 and tirzepatide is $229. The quarterly tab bills $299 and $479 every three months instead. That works out to $100 and $160 a month on a commitment. No membership fee is charged, and canceling carries no fee. HSA and FSA cards are accepted at checkout.
What it claims, and what it cites
Both drugs are compounded by a licensed 503A pharmacy. The FAQ names VialsRX in Houston as the pharmacy that fills them. Compounded drugs are not FDA-approved, and the FDA does not review them before dispensing. The seller states every batch is tested for sterility, endotoxin and potency.
Where it holds up, and where it does not
- Strength: No-contract monthly rate on both drugs
- Strength: Price stated flat across every dose
- Strength: Filling pharmacy named in the FAQ
- Strength: Refundable until a prescription is written
- Limitation: The quarterly tab is selected by default
- Limitation: No live visit with the physician
- Limitation: The reviewing physician is not named
What the evidence says about this kind of treatment
The assessment above is about Rylo Health. These are about the drugs it sells, and they are traced to the primary literature.
- Right for
- A reader who wants one monthly figure that holds through the dose ladder.
- Wrong for
- A reader who wants a live visit with a physician before a prescription is written.
How Rylo Health compares
| Seller | Who it suits | Go |
|---|---|---|
 Somira Health | Readers who want the pharmacy and the rate named before the intake | See Somira Health → |
 Rewinding RX | Readers who want a fixed figure and the doses it covers listed | See Rewinding RX → |
 Liberty | A reader who wants to know what kind of facility made the vial, and will accept a mid-market rate to get that in writing. | See Liberty → |
More GLP-1 telehealth sellers reviews: OmzoOndra HealthOnlyRxOnyx Weight LossOpen Water RxOptimized Health
Sponsored alternative
Bodybuilding Health+
A reader unwilling to prepay a year before seeing how the drug goes
Check Bodybuilding Health+ availability →Frequently asked
- What does Rylo Health charge each month?
- $139 for semaglutide and $229 for tirzepatide, month to month. Both figures hold at every dose on the ladder.
- Why does the page show $100 first?
- The quarterly tab opens by default and bills $299 every three months. The no-contract rate sits on the monthly tab beside it.
- Which pharmacy fills the order?
- VialsRX in Houston, according to the seller's FAQ. It is a licensed 503A compounding pharmacy.
- Is Rylo Health legit?
- Rylo Health is a GLP-1 telehealth sellers service. Its stated availability: All 50 states. What our record does not establish: whether it bills insurance and how its intake works. Ask for those in writing before you pay.
- Is Rylo Health expensive compared with other GLP-1 telehealth sellers?
- Rylo Health publishes a starting figure of $139/mo. Across the 368 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $49 to $449 with a median of $189, which puts Rylo Health below the median, toward the cheaper end. The other 20 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.