Updated September 2026One named prescriber, seven statesZYP Medical review
A one-provider clinic near Omaha that prices each order by how long the vial will last, and prints the arithmetic.
The verdict
ZYP Medical is a small practice built around one family nurse practitioner, and it is unusually frank that the price of a refill moves with the dose. Its starter plans are $399 for ten weeks of compounded semaglutide and $450 for two months of tirzepatide, and every new patient books a paid consult first.
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- Category
- GLP-1 telehealth
- Molecule
- Semaglutide · Tirzepatide
- Form
- Injection · Oral
- States
- 6
- Injection
- From $173/mo
- Oral
- From $250/mo
- Dose published
- Yes
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
- Pharmacy
- Not named
- Availability
- Nebraska, Iowa, South Dakota, Minnesota, Kansas, Colorado and Arizona
ZYP Medical is a clinic based in Gretna, Nebraska, that sees patients in person near Omaha and by telehealth in Nebraska, Iowa, South Dakota, Minnesota, Kansas, Colorado and Arizona. Alongside weight loss it offers testosterone therapy, urgent care, NAD+, peptides, IV hydration and lab testing, and its GLP-1 menu covers injectable semaglutide and tirzepatide plus two needle-free tirzepatide tablets.
Who writes the prescription, and what do they see?
The prescriber is named on the page: Josh Peterson, a family nurse practitioner, who reviews the intake ahead of the visit and writes a prescription only when he judges treatment appropriate. Patients text him directly rather than going through a call center, and the site says the consult fee pays for his clinical time, not for a prescription.
Treatment starts with a booked consult, either an hour-long Deep Dive for people new to these drugs or a thirty-minute Power Consult for those who have taken them before, and a prescription can go out the same day. Medication ships from licensed 503A compounding pharmacies in three to five business days, with supplies, cold-pack shipping and unlimited messaging counted inside the medication price. All sales are final, consult fees are not returned once the visit has happened, and a prepaid plan canceled before a later vial ships carries only a capped partial refund.
What happens when the dose goes up?
The tirzepatide starter covers four weeks at 2.5 mg and four at 5 mg, with a check-in at week seven before the reorder. The semaglutide starter steps from 0.25 mg to 0.5 mg to 1 mg across ten weeks, all drawn from a single vial. After the starter, the FAQ explains that a higher dose empties the same vial sooner, so each order is priced on how long it will actually last. A dose change made mid-supply is explained to the patient before it happens, not after. The page also offers in-between doses, giving 3.5 mg of tirzepatide as its example.
What the price includes
The product page prices the semaglutide starter at "$160/month" and "$399 for the 10-week starter plan, paid in full", which comes to about $173 a calendar month, and the tirzepatide starter at "$225/month" and "$450 for the 2-month starter plan". The dissolving tirzepatide tablet is $250 a month for a 30-day supply. Refills are priced by dose and quantity rather than at a flat rate, with semaglutide capped at $350 per order, and the consult adds a one-time $50 for the Deep Dive or $29.99 for the Power Consult. The hero banner still shows a lower starting figure than the plan cards beneath it, and Affirm financing costs more in total than paying up front.
What it claims, and what it cites
Both injectables and both tablets are compounded and used off-label, and the site says plainly that none of them is FDA-approved and that the brand products are considered first-line treatment for obesity. The standard formulation includes vitamin B6, which the page says is there for nausea and plays no part in the weight loss, with a B12 and glycine version available at extra cost. The pharmacies are described as licensed 503A compounders that test each batch for potency, though none is named.
Where it holds up, and where it does not
- Strength: Prescribing nurse practitioner named, reachable by text
- Strength: Dose-based pricing explained with its arithmetic
- Strength: In-between doses available, not just fixed steps
- Strength: Month-to-month supplies offered at every dose
- Limitation: Paid consult required before any prescription
- Limitation: Refill prices depend on dose, not published
- Limitation: Serves seven states, per the page
- Limitation: All sales final and no pharmacy named
What the evidence says about this kind of treatment
The assessment above is about ZYP Medical. These are about the drugs it sells, and they are traced to the primary literature.
- Right for
- A patient in one of the seven states who wants a named clinician on text and is willing to pay per order as the dose changes.
- Wrong for
- Someone living outside the seven listed states, or anyone who wants one flat monthly charge that holds as the dose rises.
How ZYP Medical compares
| Seller | Who it suits | Go |
|---|---|---|
 Dr. Gillis' Wellness Center | Maine patients who want a named physician and in-person follow-up | See Dr. Gillis' Wellness Center → |
| Big Easy Weight Loss | Readers who can pay a block up front and want the new-patient reduction | See Big Easy Weight Loss → |
| Center for Medical Weight Loss (CMWL) | Buyers who want a named medical director and a rate that holds at every dose | See Center for Medical Weight Loss (CMWL) → |
More GLP-1 telehealth sellers reviews: Zappy HealthZealthyZera HealthZeussZipHealthPepton Health
Sponsored alternative
SkinnyRx
Readers choosing tirzepatide, the one line with a published standing rate
Check SkinnyRx availability →Frequently asked
- What does ZYP Medical charge to start?
- The semaglutide starter is $399 for ten weeks, paid in full, and the tirzepatide starter is $450 for two months, with a one-time consult first at $50 for the hour-long visit or $29.99 for the shorter one.
- Why does the price change after the starter plan?
- Each order is priced on how long the vial will last at the patient's dose, so a higher dose makes the same order cover fewer weeks, and semaglutide orders are capped at $350.
- Is there a needle-free option?
- Yes, a tirzepatide tablet that dissolves under the tongue costs $250 a month, and a chewable tirzepatide tablet is sold as well.
- Is ZYP Medical legit?
- ZYP Medical is a GLP-1 telehealth sellers service. Its stated availability: Nebraska, Iowa, South Dakota, Minnesota, Kansas, Colorado and Arizona. What our record does not establish: whether it bills insurance and how its intake works. Ask for those in writing before you pay.
- Is ZYP Medical expensive compared with other GLP-1 telehealth sellers?
- ZYP Medical publishes a starting figure of $173/mo. Across the 399 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $49 to $525.42 with a median of $189, which puts ZYP Medical below the median, toward the cheaper end. The other 58 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.