Updated September 2026A year up front, or a renewalHe & She MD review
Both injection rates are annual plans billed in a single payment, and the oral figure is an introductory rate that renews twenty percent higher.
The verdict
He & She MD advertises $99 a month for injected semaglutide and $159 for tirzepatide, read August 2026, and both require a year paid at once — $1,188 and $1,908. Its oral line runs $199 for six months and then renews at $239.
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- Category
- GLP-1 telehealth
- Molecule
- Semaglutide · Tirzepatide
- Form
- Injection · Oral
- States
- 50
- Injection
- From $99/mo
- Oral
- From $239/mo
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
- Availability
- 50 states
He & She MD sells both molecules by injection on annual plans billed up front, alongside an oral program priced as an introductory half-year that renews at a higher rate, with coverage across 50 states.
Who writes the prescription, and what do they see?
A prescription precedes dispensing, and the pages present program cards and footnotes rather than describing who reviews a case or how often. The oral line's renewal terms live in a footnote rather than on the card.
Annual prepay at a low headline is a defensible offer, and the totals are published rather than hidden. What the pages do less well is separate the two numbers in the banner, where a struck-through monthly figure and an annual one sit in the same sentence as though they were alternatives.
What happens when the dose goes up?
Nothing published states what any of these figures does as a dose climbs, which matters most on the annual plans: a buyer has committed twelve months before discovering whether the rate survives an escalation.
What the price includes
A year of injected semaglutide is $1,188 and tirzepatide $1,908, both due at signup rather than monthly. The oral program is $1,194 for its first six months and $1,434 for every six after, so a full year at the renewal rate is $2,868. Budgeting the oral at its introductory figure understates a second year by $480.
What it claims, and what it cites
The lines are compounded rather than manufactured, prepared to order by a pharmacy the pages do not name, and the FDA does not review a compounded preparation before it is dispensed.
Where it holds up, and where it does not
- Strength: Annual totals are published, not just rates
- Strength: Coverage across 50 states
- Strength: An oral program is offered separately
- Strength: The renewal rate appears in a footnote
- Limitation: Both injection rates need a year at once
- Limitation: The oral renews about 20% higher
- Limitation: The banner shows two prices in one line
- Limitation: Refunds inside an annual term are unstated
What the evidence says about this kind of treatment
The assessment above is about He & She MD. These are about the drugs it sells, and they are traced to the primary literature.
- Right for
- A reader who can pay a year in advance and wants the annual total published rather than implied.
- Wrong for
- A reader reading the oral $199 as a rate that holds, or anyone who cannot commit twelve months at signup.
How He & She MD compares
| Seller | Who it suits | Go |
|---|---|---|
 Try Ageless | Readers willing to price the same product twice before buying it once | See Try Ageless → |
| MEDVi | Readers who want the injected line, where the card figure is the medicine's figure | See MEDVi → |
| Roboclinic | Readers ready to commit a full year and wanting the discount that buys | See Roboclinic → |
More GLP-1 telehealth sellers reviews: Direct MedsDoctorAdamDrBrainRxDreamHug MedicalDudeMedsEdessa
Sponsored alternative
Synergy Rx
A reader who wants the oral and injectable rates for both molecules stated up front rather than after an intake form.
Check Synergy Rx availability →Frequently asked
- What does $99 a month actually require?
- A year paid in a single payment of $1,188. There is no month-to-month route to that figure.
- Does the oral price hold?
- No. $199 covers six months, after which the program renews at $1,434 per six months, which is $239 a month.
- What does a full year of tirzepatide cost?
- $1,908, billed up front at signup rather than spread across the year.
- Is He & She MD legit?
- He & She MD is a GLP-1 telehealth sellers service. Its stated availability: 50 states. What our record does not establish: whether it bills insurance and how its intake works. Ask for those in writing before you pay.
- Is He & She MD expensive compared with other GLP-1 telehealth sellers?
- He & She MD publishes a starting figure of $99/mo. Across the 188 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $76 to $369 with a median of $179, which puts He & She MD below the median, toward the cheaper end. The other 12 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.