Open Water Rx review
Both figures are stated as flat monthly prices, and no code is needed to reach either.
The verdict
Open Water Rx publishes $169 a month for compounded semaglutide and $219 for tirzepatide. The site calls the tirzepatide figure the flat all-inclusive price. No code is needed for either.
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- Category
- GLP-1 telehealth
- Molecule
- Semaglutide · Tirzepatide
- Form
- Injection
- From
- From $169/mo
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
Open Water Rx sells both molecules by injection, with an all-inclusive framing covering provider review, medication if prescribed, and shipping.
Who writes the prescription, and what do they see?
Provider review is named as included, and the figure is conditional on medication being prescribed. Both are stated. The clinician is not otherwise described.
An all-inclusive figure is a stronger commitment than a headline rate usually carries. Provider review, medication if prescribed and shipping are named inside it, so a reader can hold the seller to the list.
What happens when the dose goes up?
Nothing is published about dose on either main line. Two further programs exist — a lower-dose titration plan at $179 and an oral option at $279 — and neither names its molecule, so neither can be priced as a drug.
What the price includes
Six months at $169 is $1,014 and tirzepatide at $219 is $1,314. Neither figure depends on a code. The site states the tirzepatide figure is all-inclusive, and the semaglutide line carries the same framing.
What it claims, and what it cites
Both main lines are compounded. A pharmacy prepares them. The FDA does not review them before dispensing. No pharmacy is named.
Where it holds up, and where it does not
- Strength: No code needed for either figure
- Strength: Provider review and shipping included
- Strength: Tirzepatide stated flat and all-inclusive
- Limitation: No compounding pharmacy is named
- Limitation: Two further programs name no molecule
- Limitation: No dose behavior is published
- Limitation: No state coverage list is recorded
What the evidence says about this kind of treatment
The assessment above is about Open Water Rx. These are about the drugs it sells, and they are traced to the primary literature.
- Right for
- A reader who wants one all-inclusive figure with no code attached.
- Wrong for
- A reader who needs the cost at a maintenance dose stated in advance.
The evidence behind what Open Water Rx prescribes
These studies examine the medicines, not this provider. Results with approved products do not establish the quality or effectiveness of a seller’s compounded formulation.
- Cochrane Review of Semaglutide for Obesity: 18 Trials Graded
A 2025 Cochrane review pooled eighteen randomized trials. The weight figure is high certainty and smaller than the marketing, and almost everything else is graded lower.
- Tirzepatide vs Semaglutide: Which Works Better for Weight Loss?
In a 72-week randomized trial at weight-management doses, weight fell 20.2 percent on tirzepatide and 13.7 percent on semaglutide. Routine-care studies found a smaller gap, three to four points.
How Open Water Rx compares
| Seller | Who it suits | Go |
|---|---|---|
 Oak | Readers who want a flat rate without a subscription and ignore the entry figure | See Oak → |
 Obu Health | Readers who value a site that agrees with itself | See Obu Health → |
 Onyx Weight Loss | A reader inside the eight-state footprint who reads what each card actually names | See Onyx Weight Loss → |
More GLP-1 telehealth sellers reviews: AJ PeptideAmbiante Health & WellnessAurelius Health GroupAVArxBasal HealthBetter MedSpa
Sponsored alternative
SkinnyRx
Readers choosing tirzepatide, the one line with a published standing rate
Check SkinnyRx availability →Frequently asked
- What are the current figures?
- $169 a month for semaglutide and $219 for tirzepatide.
- Do I need a code?
- No. Both figures are base prices, and the site calls $219 the flat all-inclusive price for tirzepatide.
- What are the other two programs?
- A lower-dose titration plan at $179 and an oral option at $279. Neither names its molecule.
- Is Open Water Rx expensive compared with other GLP-1 telehealth sellers?
- Open Water Rx publishes a starting figure of $169/mo. Across the 402 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $49 to $525.42 with a median of $190, which puts Open Water Rx below the median, toward the cheaper end. The other 178 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.