PreventiveMD review
It carries orforglipron alongside the usual pair, and its lowest figures are twelve-month plans paid up front.
The verdict
PreventiveMD charges $119 for a one-month supply of compounded semaglutide and $139 for tirzepatide, both described as all-in. Its $83 and $97 headlines are twelve-month plans, and it also lists orforglipron from $149 — a third molecule most sellers in this category do not carry at all.
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- Category
- GLP-1 telehealth
- Molecule
- Orforglipron · Semaglutide · Tirzepatide
- Form
- Injection · Oral
- States
- 36
- Injection
- From $119/mo
- Oral
- From $198/mo
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
PreventiveMD sells compounded semaglutide and compounded tirzepatide by injection on one, three, six and twelve-month supplies, describing every figure as all-in. It also lists orforglipron from $149 plus a $49 monthly membership, which applies on brand plans. Thirty-six states are served.
Who writes the prescription, and what do they see?
Treatment is arranged remotely and a prescription precedes dispensing. The homepage carries the figures and the all-in claim rather than a description of the clinical process behind them, and the brand pathway is described as running through an approved oral tablet dispensed by a manufacturer's own service.
Carrying three molecules is the unusual part. Orforglipron is an oral small-molecule agent rather than a peptide, and a seller offering it is offering a different route rather than another version of the same one. What that route costs here is stated, which is more than most sellers manage for the drugs they do carry.
What happens when the dose goes up?
The price does not move with the dose; only the length of the supply moves it. That answers the question most sellers leave open, and it means the ladder a reader has to read is a ladder of terms rather than milligrams.
What the price includes
Semaglutide is $119 for one month, $286 for three, $536 for six and $999 for twelve, which is where the $83 comes from. Tirzepatide is $139, $334, $626 and $1,168, the last of which is the $97. The all-in description is the claim doing the work — it says the number is not a medication rate with fees to follow. Orforglipron is the exception: $149 for the medication plus the $49 membership is $198 a month.
What it claims, and what it cites
The semaglutide and tirzepatide are compounded, prepared by a pharmacy rather than manufactured and reviewed as finished products, so neither is FDA-approved and neither is assessed for safety, efficacy or quality before dispensing. The orforglipron pathway is described as an approved tablet dispensed through a manufacturer's own service, which is a different regulatory footing and worth separating from the compounded lines.
Where it holds up, and where it does not
- Strength: Carries a third molecule most sellers do not
- Strength: Both compounded figures described as all-in
- Strength: Brand and compounded routes priced separately
- Limitation: The headline figures need a year paid up front
- Limitation: A $49 membership applies on brand plans
- Limitation: Fourteen states are not served
What the evidence says about this kind of treatment
The assessment above is about PreventiveMD. These are about the drugs it sells, and they are traced to the primary literature.
- Right for
- A reader interested in orforglipron, which most sellers in this category do not offer at all.
- Wrong for
- A reader comparing the $83 headline against a month-to-month rate elsewhere.
The evidence behind what PreventiveMD prescribes
These studies examine the medicines, not this provider. Results with approved products do not establish the quality or effectiveness of a seller’s compounded formulation.
- What Is Orforglipron? A Daily GLP-1 Tablet That Is Not a Peptide
A small-molecule daily tablet, not a peptide. Over 72 weeks in 3,127 adults, weight fell 11.2% on the top dose against 2.1% on placebo. No trial has compared it against an injection.
- Cochrane Review of Semaglutide for Obesity: 18 Trials Graded
A 2025 Cochrane review pooled eighteen randomized trials. The weight figure is high certainty and smaller than the marketing, and almost everything else is graded lower.
- Tirzepatide vs Semaglutide: Which Works Better for Weight Loss?
In a 72-week randomized trial at weight-management doses, weight fell 20.2 percent on tirzepatide and 13.7 percent on semaglutide. Routine-care studies found a smaller gap, three to four points.
How PreventiveMD compares
| Seller | Who it suits | Go |
|---|---|---|
 Alan Meds | A reader ready to prepay six months who wants the full-dose price in view before the intake. | See Alan Meds → |
 Zera Health | A reader who budgets from the monthly rate printed beside the first-month offer. | See Zera Health → |
 DoctorAdam | A reader weighing a tablet against an injection who wants the decision to be about the routine rather than the cost. | See DoctorAdam → |
More GLP-1 telehealth sellers reviews: AHBARxAlegro HealthAlinwellAllara HealthAlloyAlternate Health Club
Sponsored alternative
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Readers choosing tirzepatide, the one line with a published standing rate
Check SkinnyRx availability →Frequently asked
- What is orforglipron?
- An oral small-molecule GLP-1 agent rather than a peptide, which makes it a different route from the injections most of this category sells. PreventiveMD lists it from $149.
- Does the $49 membership apply to me?
- It applies on brand plans, which here means orforglipron: $149 for the medication plus $49 is $198 a month. The compounded lines are described as all-in.
- Is $83 what I would actually pay?
- Only on the twelve-month plan, paid as $999 up front. One month of semaglutide is $119, and the price is the same at every dose.
- Is PreventiveMD expensive compared with other GLP-1 telehealth sellers?
- PreventiveMD publishes a starting figure of $119/mo. Across the 402 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $49 to $525.42 with a median of $190, which puts PreventiveMD below the median, toward the cheaper end. The other 178 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.