Updated September 2026Four-week fills, shipping extraLean Rx review
Every plan is billed in four-week fills. The one rung without a lock-in adds shipping.
The verdict
Lean Rx charges $450 for four weeks of compounded semaglutide, plus $35 shipping. That is $485 per fill. Tirzepatide is $599 plus shipping, or $634 per fill. Fills come every four weeks, thirteen a year. So a calendar month costs $525.42 and $686.83. Both are paid in full with no commitment.
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- Category
- GLP-1 telehealth
- Molecule
- Semaglutide · Tirzepatide
- Form
- Injection
- From
- From $525.42/mo
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
Lean Rx sells compounded semaglutide and tirzepatide by injection. It sells compounded medications only. Every plan is billed in four-week fills. Longer prepaid plans lower the average cost per vial.
Who writes the prescription, and what do they see?
The first step is a brief online consultation. A medical history form follows. A licensed provider then holds a telehealth call. The provider prescribes a plan if appropriate. No provider is named.
The buyer picks a program length after the call. Four options are offered per molecule. A pay-as-you-go subscription bills every four weeks. It cannot be canceled until 24 weeks. The single four-week fill carries no commitment. Longer plans are prepaid and ship free.
What happens when the dose goes up?
A typical tirzepatide schedule is published in units, not milligrams. It runs 25 units a week for weeks one to four, then 50 units. A dose above 50 units a week needs an extra vial. That vial is billed on top, every four weeks. Dose is a price variable here.
What the price includes
This site ranks the rate a buyer pays without committing. For Lean Rx that is the four-week fill. Each fill is charged $485 for semaglutide and $634 for tirzepatide, shipping included. Thirteen fills fall in a year. Per calendar month that is $525.42 and $686.83, the figures ranked here. The pay-as-you-go rate is lower but locks in 24 weeks. The 12- and 48-week plans are lower again, paid up front. Tirzepatide costs $149 more per fill.
What it claims, and what it cites
Both products are compounded, per the seller's own FAQ. They come from state-licensed compounding pharmacies or 503B outsourcing facilities. Compounded drugs are not FDA-approved. The pharmacy is not named.
Where it holds up, and where it does not
- Strength: A no-commitment fill on both molecules
- Strength: Dosing schedule published in units
- Strength: Longer plans ship free
- Strength: The seller says outright the drugs are compounded
- Limitation: Shipping adds $35 to the no-commitment fill
- Limitation: Pay-as-you-go locks in 24 weeks
- Limitation: Higher doses cost an extra vial
- Limitation: Billing runs on four weeks, not months
What the evidence says about this kind of treatment
The assessment above is about Lean Rx. These are about the drugs it sells, and they are traced to the primary literature.
- Right for
- A buyer who wants a single fill with no subscription before choosing a plan.
- Wrong for
- A buyer on a high dose, where the extra vial raises every fill.
How Lean Rx compares
| Seller | Who it suits | Go |
|---|---|---|
| Alegro Health | Buyers trying a GLP-1 for two months before committing to a rate | See Alegro Health → |
 Gimme Care | Buyers who want the monthly price fixed while the dose climbs | See Gimme Care → |
 Spry | Buyers who can read a four-week billing cycle as thirteen charges rather than twelve | See Spry → |
More GLP-1 telehealth sellers reviews: Next VialNextMedsNiceRxNirwana HealthNoBsRxNolu
Sponsored alternative
SkinnyRx
Readers choosing tirzepatide, the one line with a published standing rate
Check SkinnyRx availability →Frequently asked
- Why $525.42 and not $450?
- The four-week fill is $450 plus a required $35 overnight shipping charge, so each fill is $485. Fills come every four weeks, thirteen a year, which is $525.42 a calendar month.
- Is there a cheaper recurring plan?
- Yes, pay-as-you-go. It bills every four weeks and cannot be canceled before 24 weeks.
- Does a higher dose cost more?
- Yes. Above 50 units a week, an extra vial is billed every four weeks.
- Is Lean Rx expensive compared with other GLP-1 telehealth sellers?
- Lean Rx publishes a starting figure of $525.42/mo. Across the 399 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $49 to $525.42 with a median of $189, which puts Lean Rx above the median. The other 58 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.