Updated September 2026Four-week cycle, not a monthEnhance MD review
Everything here is billed in four-week cycles, so a plan advertised by the month lands thirteen times a year rather than twelve.
The verdict
Enhance MD advertises $212 a month for compounded semaglutide on a twelve-month plan, delivered every four weeks — thirteen fills a calendar year, or $230 a month. The microdosing tirzepatide plan bills $169 twelve times against a forty-eight-week term, which is $184 a calendar month.
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- Category
- GLP-1 telehealth
- Molecule
- Semaglutide · Tirzepatide
- Form
- Injection
- Dose pricing
- Flat across doses
- States
- 39
- From
- $184/mo
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
- Labs
- Included
Enhance MD sells compounded semaglutide and a low-dose compounded tirzepatide as weekly injections across thirty-nine states, and the thing a reader has to hold on to is that its cycle is four weeks rather than a calendar month. The semaglutide plan ladder ran $249 month to month, $237 at three months, $224 at six and $212 at twelve. Labs, the consultation and two-day shipping are described as included at every rung.
Who writes the prescription, and what do they see?
Labs and a consultation sit inside the price rather than beside it, which is the shape a reader should want and the shape that makes a like-for-like comparison hard. A seller charging less and billing the consultation separately can look cheaper on a landing page and cost more across a year. How often the consultation repeats, and whether labs are drawn again after the first set, is not something the priced row establishes.
Treatment is arranged remotely and the medication arrives on a four-week rhythm, which sounds like a monthly subscription and is not one. Thirteen deliveries land in a calendar year rather than twelve, so the advertised figure understates the annual cost by roughly one fill. The first month is discounted to $112 on plans of three months or longer, which is a real saving and also the point at which a reader commits to the term.
What happens when the dose goes up?
The semaglutide plan is flat at all doses, so an escalation does not move the bill, and that is worth more across a year than most of the headline gaps between sellers. The tirzepatide side is the harder case: it is a low-dose tier sold on prepay only, with no one-month option offered for microdosing at all. A reader who wants to try a microdose for a single month cannot buy one here, and the shortest commitment available is three months at $189.
What the price includes
The twelve-month rung is the figure the page leads with, and it buys a forty-eight-week term rather than a calendar year. Four weeks is not a month, and the difference across the semaglutide plan is $18 a month — $212 advertised against $230 actually spent. The same arithmetic runs the other way on the microdosing plan, where twelve payments cover forty-eight weeks and the calendar-month figure is $184.
What it claims, and what it cites
Both products are compounded, so a pharmacy prepares them and no regulator reviews the finished vial before it ships. The tirzepatide plan is a microdose tier, which means a weekly dose below the maintenance doses the approved label describes. The published results for tirzepatide came from those label doses over seventy-two weeks, and a microdose was not what that trial measured.
Where it holds up, and where it does not
- Strength: Labs and consultation inside the price
- Strength: Semaglutide rate flat at every dose
- Strength: Whole plan ladder published on one page
- Limitation: Cycle is four weeks, not a month
- Limitation: Microdose tier is prepay only
- Limitation: Lowest rung needs a forty-eight-week term
What the evidence says about this kind of treatment
The assessment above is about Enhance MD. These are about the drugs it sells, and they are traced to the primary literature.
- Right for
- A reader who wants the labs and the consultation inside one figure, and who can hold the four-week cycle in mind when comparing it with a monthly rate elsewhere.
- Wrong for
- A reader who wants to try a microdose for one month, because the low-dose tirzepatide tier is sold on prepay terms with no single-month option.
How Enhance MD compares
| Seller | Who it suits | Go |
|---|---|---|
 BioGlow Health | A reader who wants to see the whole ladder before starting, and who can work out which rung they are likely to sit on for most of a year. | See BioGlow Health → |
 Pallas Health | A reader who expects to stay past the first quarter and wants provider check-ins inside the price rather than billed against each visit. | See Pallas Health → |
| Idgie Health | A reader who wants a seller to say plainly that a microdose is an off-label use before taking a payment for one. | See Idgie Health → |
More GLP-1 telehealth sellers reviews: KERNX HealthLean MedsLibertyMaximusNextMedsNova
Sponsored alternative
Synergy Rx
A reader who wants the oral and injectable rates for both molecules stated up front rather than after an intake form.
Check Synergy Rx availability →Frequently asked
- Why does this site show $230 rather than the advertised $212?
- Because the plan delivers every four weeks. Thirteen fills land in a calendar year rather than twelve, so $212 a fill is $229.67 a calendar month, and that is the figure the boards here rank on.
- What does the price include?
- Labs, the consultation and two-day shipping are described as included at every rung of the semaglutide plan. That is worth holding on to when comparing it with a seller that bills a consultation separately.
- Can the microdosing tirzepatide plan be bought monthly?
- No. The low-dose tier is offered on three, six and twelve-month prepay terms at $189, $179 and $169, and no one-month option is offered for microdosing at all.
- Is Enhance MD expensive compared with other GLP-1 telehealth sellers?
- Enhance MD publishes a starting figure of $184/mo. Across the 32 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $76 to $299 with a median of $139, which puts Enhance MD above the median. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.