Onyx Weight Loss review
The ninety-nine dollar plan on the weight-loss page is a different medication entirely.
The verdict
Onyx Weight Loss publishes a standard GLP-1 plan at $228 a month and a dual GLP-1 and GIP plan from $280. The $99 card on the same page is Amlexanox, which is not a GLP-1.
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- Category
- GLP-1 telehealth
- Molecule
- Semaglutide · Tirzepatide
- Form
- Injection
- States
- 8
- From
- From $228/mo
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
- Availability
- 8 states
Onyx Weight Loss sells GLP-1 and dual-agonist plans across eight states. A third plan on the same page uses a different drug class.
Who writes the prescription, and what do they see?
A prescription precedes dispensing. The pages name plans rather than clinicians. What the plans contain is named, which is how the mismatch on the lowest card becomes visible.
Three cards sit together and one of them is a different treatment. A reader scanning for a price sees $99 first. Nothing on the layout separates the drug classes.
What happens when the dose goes up?
A GLP-1 microdosing plan is offered as a low-dose gradual start. Nothing states what either main plan costs at a higher dose. The dual-agonist figure is described as an entry tier.
What the price includes
The standard GLP-1 plan is $228 a month, which is $1,368 over six months. The dual-agonist plan starts at $280 and includes medication and supplies. The $99 card belongs to Amlexanox and should not enter a GLP-1 comparison at all.
What it claims, and what it cites
The GLP-1 lines are compounded. A pharmacy prepares them. The FDA does not review them before dispensing. Amlexanox is a different drug with a different purpose.
Where it holds up, and where it does not
- Strength: Medication and supplies inside the dual plan
- Strength: A low-dose gradual-start option exists
- Strength: Coverage recorded across eight states
- Limitation: A non-GLP-1 card sits beside the GLP-1 plans
- Limitation: Its $99 is the first figure a reader meets
- Limitation: The dual figure is an entry tier only
- Limitation: Forty-two states are not served
What the evidence says about this kind of treatment
The assessment above is about Onyx Weight Loss. These are about the drugs it sells, and they are traced to the primary literature.
- Right for
- A reader in a served state who checks which drug a card names.
- Wrong for
- A reader comparing the $99 against a GLP-1 price.
The evidence behind what Onyx Weight Loss prescribes
These studies examine the medicines, not this provider. Results with approved products do not establish the quality or effectiveness of a seller’s compounded formulation.
- Cochrane Review of Semaglutide for Obesity: 18 Trials Graded
A 2025 Cochrane review pooled eighteen randomized trials. The weight figure is high certainty and smaller than the marketing, and almost everything else is graded lower.
- Tirzepatide vs Semaglutide: Which Works Better for Weight Loss?
In a 72-week randomized trial at weight-management doses, weight fell 20.2 percent on tirzepatide and 13.7 percent on semaglutide. Routine-care studies found a smaller gap, three to four points.
How Onyx Weight Loss compares
| Seller | Who it suits | Go |
|---|---|---|
 PlexusDx | A reader who will scroll past the entry card to find a product with a name | See PlexusDx → |
 Open Water Rx | Readers who want one all-inclusive figure with no code attached | See Open Water Rx → |
 Oak | Readers who want a flat rate without a subscription and ignore the entry figure | See Oak → |
More GLP-1 telehealth sellers reviews: ZealthyZera HealthZeussZipHealthZYP Medical10Rx
Sponsored alternative
SkinnyRx
Readers choosing tirzepatide, the one line with a published standing rate
Check SkinnyRx availability →Frequently asked
- What is the $99 plan?
- Amlexanox, which is not a GLP-1. The standard GLP-1 plan on the same page is $228 a month.
- What does the dual-agonist plan cost?
- From $280 a month, with medication and supplies included. That figure is an entry tier.
- Where does Onyx operate?
- Eight states are recorded in its coverage list.
- Is Onyx Weight Loss legit?
- Onyx Weight Loss is a GLP-1 telehealth sellers service. Its stated availability: 8 states. What our record does not establish: whether it bills insurance and how its intake works. Ask for those in writing before you pay.
- Is Onyx Weight Loss expensive compared with other GLP-1 telehealth sellers?
- Onyx Weight Loss publishes a starting figure of $228/mo. Across the 402 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $49 to $525.42 with a median of $190, which puts Onyx Weight Loss above the median. The other 178 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.