Silhouette MD review
Both injections are advertised as a lowest tier. Both tablets cost substantially more and carry no such qualifier.
The verdict
Silhouette MD publishes as low as $149 a month for injected semaglutide and $299 for tirzepatide. The tablets are $263 and $325.
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- Category
- GLP-1 telehealth
- Molecule
- Semaglutide · Tirzepatide
- Form
- Injection · Oral
- Injection
- From $149/mo
- Oral
- From $263/mo
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
Silhouette MD sells both molecules as an injection and as an oral. Four lines carry a figure. Only the injections are qualified.
Who writes the prescription, and what do they see?
A prescription is issued before dispensing. Nothing describes who writes it or how often a case is reviewed.
The gap between the two routes is the useful fact. A reader choosing the tablet pays a premium of $114 or $26 depending on molecule.
What happens when the dose goes up?
Nothing published says what either injection becomes at a higher dose. The as-low-as wording implies movement without naming it.
What the price includes
Six months at $149 is $894 at best, and at $299 is $1,794. The tablets are $1,578 and $1,950 over the same period, and neither carries a lowest-tier caveat.
What it claims, and what it cites
Every line is compounded. A pharmacy prepares them. The FDA reviews none of them before they are dispensed.
Where it holds up, and where it does not
- Strength: Four lines all carry a figure
- Strength: Tablet prices are unqualified
- Strength: Both molecules in both routes
- Limitation: Both injection figures are a floor
- Limitation: The semaglutide tablet costs $114 more
- Limitation: No milligram published anywhere
- Limitation: The states served are not listed
What the evidence says about this kind of treatment
The assessment above is about Silhouette MD. These are about the drugs it sells, and they are traced to the primary literature.
- Right for
- A reader who wants an unqualified number and will pay the tablet premium to get one.
- Wrong for
- A reader assuming the tablet is the economical choice.
The evidence behind what Silhouette MD prescribes
These studies examine the medicines, not this provider. Results with approved products do not establish the quality or effectiveness of a seller’s compounded formulation.
- Cochrane Review of Semaglutide for Obesity: 18 Trials Graded
A 2025 Cochrane review pooled eighteen randomized trials. The weight figure is high certainty and smaller than the marketing, and almost everything else is graded lower.
- Tirzepatide vs Semaglutide: Which Works Better for Weight Loss?
In a 72-week randomized trial at weight-management doses, weight fell 20.2 percent on tirzepatide and 13.7 percent on semaglutide. Routine-care studies found a smaller gap, three to four points.
How Silhouette MD compares
| Seller | Who it suits | Go |
|---|---|---|
 Somi Health | Readers who want the dose question answered in writing before anything else | See Somi Health → |
| Pepton Health | Readers who will create an account before deciding anything | See Pepton Health → |
 Auren Rx | Readers who want a cancel-anytime subscription with the no-commitment rate printed beside it | See Auren Rx → |
More GLP-1 telehealth sellers reviews: TOM Weight LossTonik WellnessTransparent MedsTrava HealthTrellis VitalityTrillium Meds
Sponsored alternative
SkinnyRx
Readers choosing tirzepatide, the one line with a published standing rate
Check SkinnyRx availability →Frequently asked
- Why are the tablets dearer?
- The page does not say. It prices them higher and qualifies only the injections.
- Is $149 a real rate?
- It is the lowest advertised tier. What sits above it is unpublished.
- What does six tablet months cost?
- $1,578 for semaglutide and $1,950 for tirzepatide.
- Is Silhouette MD expensive compared with other GLP-1 telehealth sellers?
- Silhouette MD publishes a starting figure of $149/mo. Across the 402 GLP-1 telehealth sellers we review that publish a single monthly figure, those run $49 to $525.42 with a median of $190, which puts Silhouette MD below the median, toward the cheaper end. The other 178 GLP-1 telehealth sellers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.